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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1E
All Species:
20
Human Site:
S400
Identified Species:
33.85
UniProt:
P49674
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49674
NP_001885.1
416
47315
S400
L
T
G
R
Q
E
V
S
R
I
P
A
S
Q
T
Chimpanzee
Pan troglodytes
XP_515128
385
44007
R369
T
S
P
R
A
I
S
R
V
D
R
E
R
K
T
Rhesus Macaque
Macaca mulatta
XP_001113761
317
36681
D302
F
G
A
S
R
A
A
D
D
A
E
R
E
R
R
Dog
Lupus familis
XP_850168
416
47320
S400
L
T
G
R
Q
E
V
S
R
I
S
A
S
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
S400
L
T
G
R
Q
E
V
S
R
L
A
A
S
Q
T
Rat
Rattus norvegicus
P97633
325
37477
A310
Q
K
A
A
Q
Q
A
A
S
S
S
G
Q
G
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLL1
416
47453
S400
L
T
G
R
Q
E
V
S
R
I
S
A
S
Q
T
Frog
Xenopus laevis
Q5BP74
415
47421
S393
L
T
S
R
Q
D
T
S
R
M
S
T
S
Q
I
Zebra Danio
Brachydanio rerio
Q6P3K7
409
46813
S393
L
T
G
R
Q
D
T
S
R
M
S
T
S
Q
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76324
440
47939
Y400
T
N
S
S
R
P
P
Y
D
T
P
E
R
R
P
Honey Bee
Apis mellifera
XP_395574
413
47530
E391
A
S
G
T
G
G
Q
E
R
R
V
S
M
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779963
435
49455
G400
P
V
Q
R
G
D
Y
G
R
L
A
T
P
Y
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
N418
S
R
G
V
I
P
R
N
S
P
G
E
A
G
K
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
Q416
P
Q
P
Q
Q
L
Q
Q
Q
P
N
G
Q
R
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
72.5
99.2
N.A.
98.8
56.9
N.A.
N.A.
97.3
84.3
84.3
N.A.
62.7
67.5
N.A.
67.5
Protein Similarity:
100
92.5
75
99.2
N.A.
99
65.8
N.A.
N.A.
98.5
88.4
88.6
N.A.
72.9
77.4
N.A.
75.4
P-Site Identity:
100
13.3
0
93.3
N.A.
86.6
6.6
N.A.
N.A.
93.3
53.3
60
N.A.
6.6
13.3
N.A.
13.3
P-Site Similarity:
100
26.6
13.3
93.3
N.A.
93.3
20
N.A.
N.A.
93.3
66.6
73.3
N.A.
20
33.3
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
46.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
8
8
8
15
8
0
8
15
29
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
22
0
8
15
8
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
29
0
8
0
0
8
22
8
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
50
0
15
8
0
8
0
0
8
15
0
15
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
0
22
0
0
0
0
8
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
0
8
8
% K
% Leu:
43
0
0
0
0
8
0
0
0
15
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
15
0
0
8
0
0
% M
% Asn:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
8
% N
% Pro:
15
0
15
0
0
15
8
0
0
15
15
0
8
0
15
% P
% Gln:
8
8
8
8
58
8
15
8
8
0
0
0
15
43
8
% Q
% Arg:
0
8
0
58
15
0
8
8
58
8
8
8
15
29
8
% R
% Ser:
8
15
15
15
0
0
8
43
15
8
36
8
43
0
8
% S
% Thr:
15
43
0
8
0
0
15
0
0
8
0
22
0
0
36
% T
% Val:
0
8
0
8
0
0
29
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _